Stroke Summit 2026 | March 30-31, 2026

Neural Circuit Development

Neural circuit development explores how networks of neurons form, connect, and refine their communication pathways throughout growth and maturation. During early development, neurons extend axons and dendrites guided by chemical signals, cell adhesion molecules, and environmental cues that determine proper direction and target location. Synapses form when neuronal connections are established and begin to transmit electrical and chemical signals. As the brain matures, neural circuits undergo elimination of weaker connections and strengthening of frequently used pathways, shaping sensory perception, movement control, and cognitive abilities. Genetic factors, molecular signaling proteins, and external experiences influence the pattern of circuitry formation. Development continues through adolescence and adulthood as circuits adapt to learning processes, environmental conditions, and neural activity patterns. Abnormalities in circuit development can affect communication between brain regions and contribute to various neurological conditions.

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